以甲基为营养（Methylotrophic）
| 底物利用类型和反应 Substrate utilization and reactions | 标准吉布斯自由能 △_G_0 (kj/mol CH4) | 产甲烷古菌 Methanogens | | -------------------------------------------------------------- | --------------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------ | | →3CH_4+CO_2+2H_2O$ | −105 | Methanosarcinales：_Halomethanococcus_、_Methanococcoides_、_Methanohalobium_、_Methanolobus_、_Methanomethylovorans_、_Methanosalsum_、_Methanosarcina_、_Methermicoccus_ | | +H_2→CH_4+H_2O$ | −113 | Methanobacteriales：_Methanobacterium_、_Methanosphaera_ Methanomassiliicoccales：_Methanomassiliicoccus_ | | (CH_3)_2S+3H_2O→3CH_4+CO_2+H_2S$ | −49 | Methanosarcinales：_Methanolobus_、_Methanomethylovorans_、_Methanosalsum_、_Methanosarcina_ | | +2H_2O→3CH_4+CO_2+4NH_3$ | −75 | Methanosarcinales：_Methanococcoides_、_Methanohalophilus_、_Methanolobus_、_Methanomethylovorans_、_Methanosalsum_、_Methanosarcina_、_Methermicoccus_ | | (CH_3)_2NH+2H_2O→3CH_4+CO_2+2NH_3$ | −73 | Methanosarcinales：_Methanococcoides_、_Methanohalophilus_、_Methanolobus_、_Methanomethylovorans_、_Methanosarcina_ | | (CH_3)_3N+6H_2O→9CH_4+3CO_2+4NH_3$ | −74 | Methanosarcinales：_Methanococcoides_、_Methanohalophilus_、_Methanolobus_、_Methanomethylovorans_、_Methanosarcina_、_Methermicoccus_ | | (CH_3)_3N+CH_2COO^−+2H_2O→4(CH_3)_2NH+CH_2COO^−+3CH_4+CO_2$ | −721.7 | Methanosarcinales：_Methanococcoides_ | | (CH_3)_3N+CH_2CH_2OH+6H_2O→4H_2NCH_2CH_2OH+9CH_4+3CO_2+4H^+$ | −567.6 | Methanosarcinales：_Methanococcoides_ | | (CH_3)_2NCH_2CH_2OH+2H_2O→2H_2NCH_2CH_2OH+3CH_4+CO_2$ | −140.8 | Methanosarcinales：_Methanococcoides_ |