HMG-CoA还原酶（HMGR）

称谓

3-羟基-3-甲基戊二酰辅酶A还原酶 HMG-CoA reductase

$催化反应：$

[[3-羟基-3-甲基戊二酸单酰CoA（HMG-CoA）]]+2 NADPH + 2 ^{+}$ --> [[甲羟戊酸（甲瓦龙酸，MVA）]] + 2 ^{+}$ +CoASH

-

\usepackage{chemfig}
\begin{document}

\chemfig{
-[6,0.5,,,,transparent] % 下边界支撑
	HO-[0.7,1]
		(=[2,1]O)
		(-[7.3,1.2]
			-[0.7,1]
				(<:[1.3,1]OH)
				(<[2.7,1])
				(-[7.3,1]
				-[0.7,1]
					(=[2,1]O)
					(-[7.3,1.2]SCoA
					)
				)
	)
}
+2 NADPH+2 ^{+}$

\begin{tikzpicture} 
\draw [->] (0,0) to node[above] {HMGR} (1.2,0); 
\end{tikzpicture}

\chemfig{
-[6,0.5,,,,transparent] % 下边界支撑
	HO-[0.7,1]
		(=[2,1]O)
		(-[7.3,1.2]
			-[0.7,1]
				(<:[1.3,1]OH)
				(<[2.7,1])
				(-[7.3,1]
				-[0.7,1]
					(-[7.3,1]OH
					)
				)
	)
}
+2 ^{+}$
+CoASH

\end{document}

^1