N5,N10-亚甲基四氢叶酸（5,10-methylene-THF）

称谓

5,10-methylene-THF 5,10-MTHF

^5,N^{10}-CH_2-FH_4$

3D结构

C1[C@@H]2CN(CN2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)NC(CCC(=O)O)C(=O)O

生理意义

为[[dTMP：单磷酸脱氧胸苷，胸腺嘧啶脱氧核苷酸]]提供$嘌呤C_2,C_8$

$结构式：$ $ CH_2=FH_4 $

• 维基百科

\usepackage{chemfig}
\begin{document}
\chemfig{
	N(-[4,0.3]H)-[7,0.8](-[6,0.6]NH_2)=[,0.8]N-[1,0.8](=[,0.6]O)-[3,0.8]
	(-[1,0.8]N(-[1.4,1])(-[4,0.3]5)-[3,0.8]
		(-[2,0.6]CH_2-[2,0.6]
			N(-[4,0.3]10)(-[7.3,1.3]CH_2)(-[4,0.3]10)-[2,0.6]**6(
			-
			-
			-(-[,0.6]C
				(=[4,0.7]O)
				(-[2,0.7]
					NH-[2,0.6]CH
						(-[4,0.6]HOOC)
						(-[2,0.6]CH_2
							(-[2,0.6]CH_2
								(-[2,0.6]COOH)
							)
						)
				)
			)
			-
			-
			-
		)
	)
	-[4,0.8]-[5,0.8]N(-[4,0.3]H)-[7,0.8])
	=[4,0.8]-[5,0.6]
}
\end{document}

• B站版本

\usepackage{chemfig}
\begin{document}
\chemfig{
	N=[7,0.8]C(-[6,0.6]NH_2)-[,0.8]N=[1,0.8]C(-[,0.6]OH)-[3,0.8]C
	(-[1,0.8]N(-[1.5,1]CH_2)(-[4,0.3]5)-[3,0.8]C(-[,0.3]H)
		(-[2,0.6]CH_2-[2,0.6]
			N(-[7.1,1.1])(-[4,0.3]10)-[2,0.6]**6(
			-
			-
			-(-[,0.6]C
				(=[4,0.7]O)
				(-[2,0.7]
					NH-[2,0.6]CH
						(-[4,0.6]HOOC)
						(-[2,0.6]CH_2
							(-[2,0.6]CH_2
								(-[2,0.6]COOH)
							)
						)
				)
			)
			-
			-
			-
		)
	)
	-[4,0.8]C(-[2,0.3]H_2)-[5,0.8]N(-[4,0.3]H)-[7,0.6])
	=[4,0.8]C-[5,0.6]
}
\end{document}

生理作用

适用于胸腺嘧啶环上的甲基形成