C6：6-磷酸-葡萄糖酸内脂（6-Phosphogluconolactone）

称谓

6-磷酸-葡萄糖酸内脂 6-phosphogluconolactone

3D结构

C([C@@H]1[C@H]([C@@H]([C@H](C(=O)O1)O)O)O)OP(=O)(O)O

## 分子结构

7次绘制

$结构式：$

-

\usepackage{chemfig}
\definecolor{cpk_P}{rgb}{1.00, 0.50, 0.00}     % P
\begin{document}
\chemfig[cram width=2pt]{
	[2]*6(
	%2
	(-[6,0.5]OH)(-[2,0.5]H)
	%1
	>(=[0,0.5]O)
	%O
	-O
	%5
	-(-[2]CH_2O(
		% P
		(-[0,0.35,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P,line width=2pt] (0.1,0.12)circle(6pt);}P}
		% 上边界支撑
		-[2,0.5,,,,transparent])
	))
	%4
    -(-[6,0.5,,2]HO)(-[2,0.5]H)
    %3
    <(-[2,0.5,,]OH)(-[6,0.5]H)
    -[,,,,line width=2pt](-[6,0.5]OH)
    )
}
\end{document}

-

\usepackage{chemfig}
\definecolor{cpk_P}{rgb}{1.00, 0.50, 0.00}     % P
\begin{document}
\chemfig[cram width=2pt]{
	%[:-30]
	%C4
	(-[2,0.5]H)(-[6,0.5,,2]HO)
	*6(
	%C3
	<(-[6,0.5]H)(-[2,0.5]OH)
	%C2
	-[,1,,, line width=2pt](-[2,0.5]H)(-[6,0.5]OH)
	%C1
	>(=[0,0.5]O)
	-O-
	%C5
	(-[2,0.5,,]CH_2O
		% P
		(-[0,0.35,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P,line width=2pt] (0.1,0.12)circle(6pt);}P}
		% 上边界支撑
		-[2,0.5,,,,transparent])
	)-
	)
}
\end{document}

-

\usepackage{chemfig}
\begin{document}
\chemfig[cram width=2pt]{
	%[:-30]
	%C4
	(-[2,0.5]H)(-[6,0.5,,2]HO)
	*6(
	%C3
	<(-[6,0.5]H)(-[2,0.5]OH)
	%C2
	-[,1,,, line width=2pt](-[2,0.5]H)(-[6,0.5]OH)
	%C1
	>(=[0,0.5]O)
	-O-
	%C5
	(-[2]CH_2OPO_3^{2-})
	-
	)
}
\end{document}

• P366

\usepackage{chemfig}
\begin{document}
\chemfig[cram width=2pt]{
	[2]*6(
	%2
	(-[6,0.5]OH)(-[2,0.5]H)
	%1
	>(=[0,0.5]O)
	%O
	-O
	%5
	-(-[2]CH_2OPO_3^{2-})
	%4
    -(-[6,0.5,,2]HO)(-[2,0.5]H)
    %3
    <(-[2,0.5,,]OH)(-[6,0.5]H)
    -[,,,,line width=2pt](-[6,0.5]OH)
    )
}
\end{document}

• 哈沃斯投影式

\usepackage{chemfig}
\begin{document}
\chemfig[cram width=2pt]{
	[2]*6(
	%2
	(-[6]OH)
	%1
	>(=[0]O)
	%O
	-O
	%5
	-(-[2,]CH_2-[2,]O-[2,]P
		(-[0,]OH)
		(-[2,]OH)
		(=[4,]O)
	)
	%4
    -(-[6,,,2]HO)
    %3
    <(-[2,,,]OH)
    -[,,,,line width=2pt](-[6,0.5]OH)
    )
}
\end{document}

• 维基百科

\usepackage{chemfig}
\begin{document}
\chemfig[cram width=4pt]{
	[2.65]*6(
	%2
	(<:OH)
	%1
	-(=O)
	%O
	-O
	%5
	-(<[,,,1]-[2.5,,1]O-[4,]P
		(-[6,]OH)
		(-[4,]HO)
		(=[2,]O)
	)
	%4
    -(<:[,,,2]HO)
    %3
    -(<[,,,1]OH)
    -(-[,0.5]OH)
    )
}
\end{document}

-

\usepackage{chemfig}
\begin{document}

\chemfig{
	(=[,0.8]O)
	(-[5,0.5]
		(<:[7,0.8]OH)
		(-[4,0.5]
			(<[5,0.8]HO)
			(-[3,0.5]
				(<:[4,0.8]HO)
				(-[1,0.5]
					(<[2,0.8]
						-[3.5,0.8]\fbox{P}
					)
					(-[,0.5]O
						(-[7,0.5])
					)
				)
			)
		)
	)
} 

\end{document}

产生

[[1. HMP：第一次脱氢：葡萄糖-6-磷酸脱氢酶（G6PD）]]

参与反应

[[2. HMP：6-磷酸-葡萄糖酸内脂酶（PGLS）]]