称谓
葡萄糖-6-磷酸脱氢酶 glucose 6-phosphate dehydrogenase G6PD
[[C6：葡糖-6-磷酸（glucose 6-phosphate，G6P）]]+^+$ ->[[C6：6-磷酸-葡萄糖酸内脂（6-Phosphogluconolactone）]]+$+^+$
催化反应
$化学方程式：$ -
\usepackage{chemfig}
\definecolor{cpk_P}{rgb}{1.00, 0.50, 0.00} % P
\begin{document}
\chemname{
\chemfig[cram width=2pt]{
%[:-30]
%C4
(-[2,0.5]H)(-[6,0.5,,2]HO)
*6(
%C3
<(-[6,0.5]H)(-[2,0.5]OH)
%C2
-[,1,,, line width=2pt](-[2,0.5]H)(-[6,0.5]OH)
%C1
>(-[2,0.5]H)(-[6,0.5]OH)
-O-
%C5
(-[2,0.5,,]CH_2O
% P
(-[0,0.35,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P,line width=2pt] (0.1,0.12)circle(6pt);}P}
% 上边界支撑
-[2,0.5,,,,transparent])
)-
)
}
}{glucose 6-phosphate}
\quad
+^+$
\begin{tikzpicture}
\draw [->] (0,0) to node[above] {glucose 6-phosphate dehydrogenase} (5.6,0);
\end{tikzpicture}
\quad\quad
\chemname{
\chemfig[cram width=2pt]{
%[:-30]
%C4
(-[2,0.5]H)(-[6,0.5,,2]HO)
*6(
%C3
<(-[6,0.5]H)(-[2,0.5]OH)
%C2
-[,1,,, line width=2pt](-[2,0.5]H)(-[6,0.5]OH)
%C1
>(=[0,0.5]O)
-O-
%C5
(-[2,0.5,,]CH_2O
% P
(-[0,0.35,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P,line width=2pt] (0.1,0.12)circle(6pt);}P}
% 上边界支撑
-[2,0.5,,,,transparent])
)-
)
}
}{6-phosphogluconolactone}
+$
+^+$
\end{document}^1
• P366
\usepackage{chemfig}
\begin{document}
\chemname{
\chemfig[cram width=2pt]{
[2]*6(
%2
(-[6,0.5]OH)(-[2,0.5]H)
%1
>(-[6,0.5]OH)(-[2,0.5]H)
%O
-O
%5
-(-[2]CH_2OPO_3^{2-})
%4
-(-[6,0.5,,2]HO)(-[2,0.5]H)
%3
<(-[2,0.5,,]OH)(-[6,0.5]H)
-[,,,,line width=2pt](-[6,0.5]OH)
)
}
}{glucose 6-phosphate}
\quad
+^+$
\begin{tikzpicture}
\draw [->] (0,0) to node[above] {glucose 6-phosphate dehydrogenase} (5.6,0);
\end{tikzpicture}
\quad\quad
\chemname{
\chemfig[cram width=2pt]{
[2]*6(
%2
(-[6,0.5]OH)(-[2,0.5]H)
%1
>(=[0,0.5]O)
%O
-O
%5
-(-[2]CH_2OPO_3^{2-})
%4
-(-[6,0.5,,2]HO)(-[2,0.5]H)
%3
<(-[2,0.5,,]OH)(-[6,0.5]H)
-[,,,,line width=2pt](-[6,0.5]OH)
)
}
}{6-phosphogluconolactone}
+$
+^+$
\end{document}• 哈沃斯投影式
\usepackage{chemfig}
\begin{document}
\chemfig[cram width=2pt]{
[2]*6(
%2
(-[6]OH)
%1
>(-[6]OH)
%O
-O
%5
-(-[2,]CH_2-[2,]O-[2,]P
(-[0,]OH)
(-[2,]OH)
(=[4,]O)
)
%4
-(-[6,,,2]HO)
%3
<(-[2,,,]OH)
-[,,,,line width=2pt](-[6,0.5]OH)
)
}
+^+$
\begin{tikzpicture}
\draw [->] (0,0) to node[above] {G6PD} (1,0);
\end{tikzpicture}
\chemfig[cram width=2pt]{
[2]*6(
%2
(-[6]OH)
%1
>(=[0]O)
%O
-O
%5
-(-[2,]CH_2-[2,]O-[2,]P
(-[0,]OH)
(-[2,]OH)
(=[4,]O)
)
%4
-(-[6,,,2]HO)
%3
<(-[2,,,]OH)
-[,,,,line width=2pt](-[6,0.5]OH)
)
}
+$
+^+$
\end{document}• 维基百科
\usepackage{chemfig}
\begin{document}
\chemfig[cram width=4pt]{
[2.65]*6(
%2
(<:OH)
%1
-(<:OH)
%O
-O
%5
-(<[,,,1]-[2.5,,1]O-[4,]P
(-[6,]OH)
(-[4,]HO)
(=[2,]O)
)
%4
-(<:[,,,2]HO)
%3
-(<[,,,1]OH)
-(-[,0.5]OH)
)
}
+^+$
\begin{tikzpicture}
\draw [->] (0,0) to node[above] {G6PD} (1,0);
\end{tikzpicture}
\chemfig[cram width=4pt]{
[2.65]*6(
%2
(<:OH)
%1
-(=O)
%O
-O
%5
-(<[,,,1]-[2.5,,1]O-[4,]P
(-[6,]OH)
(-[4,]HO)
(=[2,]O)
)
%4
-(<:[,,,2]HO)
%3
-(<[,,,1]OH)
-(-[,0.5]OH)
)
}
+$
+^+$
\end{document}---
-
\usepackage{chemfig}
\begin{document}
\chemfig{
(-[,0.5]OH)
(<[5,0.5]
(-[7,0.5]OH)
(-[4,0.5,,, line width=2pt]
(-[5,0.5]HO)
(>[3,0.5]
(-[4,0.5]HO)
(-[1,0.5]
(-[2,0.5]
(-[3.5,0.8]\fbox{P})
)
(-[,0.5]O
(-[7,0.5])
)
)
)
)
)
}
+^+$
\begin{tikzpicture}
\draw [->] (0,0) to node[above] {G6PD} (1,0);
\end{tikzpicture}
\chemfig{
(=[,0.8]O)
(-[5,0.5]
(<:[7,0.8]OH)
(-[4,0.5]
(<[5,0.8]HO)
(-[3,0.5]
(<:[4,0.8]HO)
(-[1,0.5]
(<[2,0.8]
-[3.5,0.8]\fbox{P}
)
(-[,0.5]O
(-[7,0.5])
)
)
)
)
)
}
+$
+^+$
\end{document}需要^{2+}$作为激活剂 受到NADPH的竞争性抑制