PEP羧化酶（PEPC）

称谓

PEP Carboxylase PEP-C PEPCase PEPC EC 4.1.1.31 PDB ID: 3ZGE 磷酸烯醇丙酮酸羧化酶

催化反应

[[C3：磷酸烯醇式丙酮酸（PEP）]]+^-$ ->[[C4：草酰乙酸（OAA，oxaloacetate）]]+$

\usepackage{chemfig}
\begin{document}

\chemfig{
	(-[3.5,0.8]\fbox{P})
	(=[6,0.5])
	(-[0.5,0.5]
		(=[2,0.5]O)
		(-[7.5,0.8]OH)
	)
}
+^-$

\begin{tikzpicture} 
\draw [->] (0,0) to node[above] {PEPC} (1,0); 
\end{tikzpicture}

\chemfig{
	(-[3.5,0.5]HO)
	(=[6,0.5]O)
	(-[0.5,0.5]
		(-[7.5,0.5]
			(=[6,0.5]O)
			(-[0.5,0.5]
				(=[2,0.5]O)
				(-[7.5,0.5]OH)
			)
		)
	)
}
+$

\end{document}

大多数PEP羧化酶只有在[[C2：乙酰CoA（Acetyl-CoA）]]的参与下才能起催化作用，而C1代谢中的【特异性PEP羧化酶】为【不依赖乙酰CoA型的酶】，编码此两种同工酶的基因只有30%左右的重复序列。

---