HK：催化反应2--果糖磷酸化

[[C6：果糖（fructose ）]]+ATP=[[C6：果糖-6-磷酸（F6P）]]+ADP

$化学方程式：$

-

\usepackage{chemfig}
\begin{document}
\chemfig[cram width=2pt]{
	%5-6
	(-[6,0.5]H)(-[0.7,1.25]O)(-[2,0.5,,3]HOCH_2)
	%4
	<[6.75,](-[6,0.5]OH)(-[2,0.5]H)
	%3
	-[,,,, line width=2pt](-[2,0.5,,2]HO)(-[6,0.5]H)
	%2
    >[1.25,](-[2,0.5]OH)(-[3.3,1.05])
	%1
	-[6,0.5]CH_2OH
}
+ATP
\begin{tikzpicture} 
\draw [->] (0,0) to node[above] {HK} (1,0);
\end{tikzpicture}
\chemfig[cram width=2pt]{
	%5-6
	(-[6,0.5]H)(-[0.7,1.25]O)(-[2,,,5]^{2-}O_3POCH_2)
	%4
	<[6.75,](-[6,0.5]OH)(-[2,0.5]H)
	%3
	-[,,,, line width=2pt](-[2,0.5,,2]HO)(-[6,0.5]H)
	%2
    >[1.25,](-[2,0.5]OH)(-[3.3,1.05])
	%1
	-[6,0.5]CH_2OH
}
+ADP
\end{document}

-

\usepackage{chemfig}
\begin{document}

\chemfig{
HO-[7,0.5]-[6,0.4]
	(-[0.75,0.8]O)
	<[6.75,0.7](-[5.5,0.5]O-[4,0.25]H)
	-[,0.5,,, line width=2pt]
	(-[2.25,0.5]HO)>[1.25,0.7](-[6,0.5]OH)(-[3.25,0.6])
	-[2,0.4]-[1,0.5]OH
} 
	
+ATP
\begin{tikzpicture} 
\draw [->] (0,0) to node[above] {HK} (1,0);
\end{tikzpicture}

\chemfig{
	(-[2,0.5]OH)
	(>[5,0.5]
		(-[3,0.6])
		(<:[7.5,0.8]OH)
		(-[5,0.5]
			(<[7,0.8]OH)
			(-[4,0.5]
				(<:[5,0.8]HO)
				(-[3,0.5]
					(-[1,0.85]O)
					(<[3,0.5]
						(-[2,0.8]\fbox{P})
					)
				)
			)
		)
	)
}

+ADP
\end{document}

生理意义

• 在患有必需果糖尿的患者中，己糖激酶将[[C6：果糖（fructose ）]]代谢为[[C6：果糖-6-磷酸（F6P）]]是代谢饮食中果糖的主要方式；这一途径在正常个体中并不显著。