0. 醛缩酶（aldolase）--果糖-1,6-二磷酸裂解

![[AldolaseScene.mp4]]

称谓

醛缩酶 aldolase

催化反应

[[C6：果糖-1,6-二磷酸（FBP）]]<->[[C3：二羟丙酮磷酸（DHAP）]]+[[C3：甘油醛 3-磷酸（PGAL；G3P）]]

$化学方程式：$

-

\usepackage{chemfig}
\definecolor{cpk_P}{rgb}{1.00, 0.50, 0.00}     % P
\definecolor{cpk_P6}{rgb}{0.50, 0.75, 0.50}     % P6
\begin{document}
\chemname{
\chemfig[cram width=2pt]{
	%5-6
	(-[6,0.5]H)(-[0.7,1.25]O)(-[2,1.25]CH_2O
				% P
				(-[0,0.35,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P,line width=2pt] (0.1,0.12)circle(6pt);}P}
				% 上边界支撑
				-[2,0.5,,,,transparent])
	)
	%4
	<[6.75,](-[6,0.5]OH)(-[2,0.5]H)
	%3
	-[,,,, line width=2pt](-[2,0.5,,2]HO)(-[6,0.5]H)
	%2
    >[1.25,](-[2,0.5]OH)(-[3.3,1.05])
	%1
	-[6,0.5]CH_2O
		% P
		(-[0,0.35,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P6,line width=2pt] (0.1,0.12)circle(6pt);}P})
}
}{fructose 1,6-bisphosphate}
\quad\quad
\begin{tikzpicture} 
\draw [<->] (0,0) to node[above] {aldolase} (1.4,0);  
\end{tikzpicture}
\quad\quad\quad\quad
\chemname{
\chemfig[atom sep=2em]{
(-[2,1.1,,,transparent]) %向上支撑
	CH_2O(
		% P
		(-[0,0.54,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P,line width=2pt] (0.1,0.12)circle(6pt);}P}
		% 上边界支撑
		-[2,0.5,,,,transparent])
	)
	-[6,]C(=O)
	-[6,]CH_2OH
}
}{dihydroxyacetone phosphate}
\quad\quad\quad\quad
+
\quad\quad\quad\quad
\chemname{
\chemfig[atom sep=2em]{
(-[2,1.1,,,transparent]) %向上支撑
	C(-[1,]H)(=[3,]O)
	-[6,]C(-[,]OH)(-[4,]H)
	-[6,]CH_2O
		% P
		(-[0,0.54,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P6,line width=2pt] (0.1,0.12)circle(6pt);}P}
		% 下边界支撑
		-[6,0.5,,,,transparent])
}
}{glyceraldehyde 3-phosphate}
\end{document}

^1

-

\usepackage{chemfig}
\definecolor{cpk_P}{rgb}{1.00, 0.50, 0.00}     % P
\definecolor{cpk_P6}{rgb}{0.50, 0.75, 0.50}     % P6
\begin{document}
\chemname{
\chemfig[cram width=2pt]{
	%5-6
		(-[6,0.5]H)
		(-[0.7,1.25]O)
			%6
			(-[2,1.25,,]CH_2O
				% P
				(-[0,0.35,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P,line width=2pt] (0.1,0.12)circle(6pt);}P}
				% 上边界支撑
				-[2,0.5,,,,transparent])
			)
	%4
	<[6.75,](-[6,0.35]-[6,0.15,,,transparent]-[0,0.13,,,transparent]{\color{pink}OH})(-[2,0.5]H)
	%3
	-[,,,, line width=2pt](-[2,0.35,,]-[2,0.15,,,transparent]-[4,0.13,,,transparent]{\color{blue}HO})(-[6,0.5]H)
	%2
    >[1.25,](-[2,0.35]-[2,0.15,,,transparent]-[0,0.13,,,transparent]{\color{green}OH})(-[3.3,1.05])
	%1
	-[6,0.5]CH_2O
	(
		% P
		(-[0,0.34,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P6,line width=2pt] (0.1,0.12)circle(6pt);}P}
		% 上边界支撑
		-[2,0.5,,,,transparent])
	)
}
}{}
\begin{tikzpicture} 
\draw [<->] (0,0) to node[above] {} (1,0);  
\end{tikzpicture}
\chemname{
\chemfig[atom sep=2em]{
(-[2,1.1,,,transparent]) %向上支撑
	CH_2O(
		% P
		(-[0,0.54,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P,line width=2pt] (0.1,0.12)circle(6pt);}P}
		% 上边界支撑
		-[2,0.5,,,,transparent])
	)
	-[6,]C(=O)
	-[6,]CH_2{\color{pink}{OH}}
}
}{}
+
\chemname{
\chemfig[atom sep=2em]{
(-[2,1.1,,,transparent]) %向上支撑
	C(-[1,]H)(=[3,]{\color{blue}O})
	-[6,]C(-[,]{\color{green}OH})(-[4,]H)
	-[6,]CH_2O
		% P
		(-[0,0.54,,,,transparent]{\chemmove{\draw[ultra thick,green,fill=cpk_P6,line width=2pt] (0.1,0.12)circle(6pt);}P}
		% 下边界支撑
		-[6,0.5,,,,transparent])
}
}{}
\end{document}

^2

-

\usepackage{chemfig}
\begin{document}
\chemname{
\chemfig[cram width=2pt]{
	%5-6
	(-[6,0.5]H)(-[0.7,1.25]O)(-[2,,,5]^{2-}O_3POCH_2)
	%4
	<[6.75,](-[6,0.5]OH)(-[2,0.5]H)
	%3
	-[,,,, line width=2pt](-[2,0.5,,2]HO)(-[6,0.5]H)
	%2
    >[1.25,](-[2,0.5]OH)(-[3.3,1.05])
	%1
	-[6,0.5]CH_2OPO_3^{2-}
}
}{fructose 1,6-bisphosphate}
\quad\quad
\begin{tikzpicture} 
\draw [<->] (0,0) to node[above] {aldolase} (1.4,0);  
\end{tikzpicture}
\quad\quad\quad\quad
\chemname{
\chemfig[atom sep=2em]{
	CH_2OPO_3^{2-}
	-[6,]C(=O)
	-[6,]CH_2OH
}
}{dihydroxyacetone phosphate}
\quad\quad\quad\quad
+
\quad\quad\quad\quad
\chemname{
\chemfig[atom sep=2em]{
	C(-[1,]H)(=[3,]O)
	-[6,]C(-[,]OH)(-[4,]H)
	-[6,]CH_2OPO_3^{2-}
}
}{glyceraldehyde 3-phosphate}
\end{document}

-

\usepackage{chemfig}
\begin{document}
\chemfig{
	(-[2,0.5]\fbox{P})
	(>[5,0.5]
		(-[3,0.6])
		(<:[7.5,0.8]OH)
		(-[5,0.5]
			(<[7,0.8]OH)
			(-[4,0.5]
				(<:[5,0.8]HO)
				(-[3,0.5]
					(-[1,0.85]O)
					(<[3,0.5]
						(-[2,0.5]\fbox{P})
					)
				)
			)
		)
	)
}

\begin{tikzpicture} 
\draw [<->] (0,0) to node[above] {aldolase} (1.4,0);  
\end{tikzpicture}

\chemfig{
	(-[3.5,0.5]
		(-[4.5,0.8]HO)
	)
	(=[6,0.8]O)
	(-[0.5,0.5]
		(-[7.5,0.8]\fbox{P})
	)
}

+\chemfig{
		(=[4.5,0.8]O)
		(-[7.5,0.5]
			(<[6,0.8]OH)
			(-[0.5,0.5]
				-[7.5,0.8]\fbox{P})
		)
}

\end{document}