整体过程
flowchart TB
acetone["丙酮
acetone"]
ketone["酮体
acetone"]
triose_phosphate["磷酸丙糖
triose phosphate"]
methylglyoxal["甲基乙二醛
methylglyoxal"]
lactaldehyde["乳醛
lactaldehyde"]
l_lactate["L-乳酸
L-lactate"]
d_lactate["D-乳酸
D-lactate"]
pyruvate["丙酮酸
pyruvate"]
s_d_lactoylglutathione["S-D-乳腺谷胱甘肽
s_d_lactoylglutathione"]
tca["三羧酸循环
TAC"]
acetone--"methylglyoxal synthase"-->methylglyoxal
ketone--"methylglyoxal synthase"-->methylglyoxal
triose_phosphate--"methylglyoxal synthase"-->methylglyoxal
methylglyoxal--"methylgyoxal reductase"-->lactaldehyde
lactaldehyde--"aldehyde dehydrogenase"-->l_lactate
l_lactate<--"L-LDH"-->pyruvate
d_lactate<--"D-LDH"-->pyruvate
methylglyoxal--"glyoxylase I"-->s_d_lactoylglutathione
s_d_lactoylglutathione--"glyoxylase II"-->d_lactate
pyruvate-->tca过程梳理
| 步骤 | 意义 | | --- | ---------------------------------------------------------------- | | 1 | [[甲基乙二醛（丙酮醛，methylglyoxal）]]的产生：[[丙酮醛酶（methylglyoxal synthase）]] | | 2 | [[甲基乙二醛（丙酮醛，methylglyoxal）]]转化为[[C3：丙酮酸（pyruvate）]] |
其中第二步分两个支路
| 步骤 | 支路1<br> | 支路2 | | --- | ---------------------------------------------- | ------------------------- | | 3 | [[甲基乙二醛还原酶（甲基乙二醇还原酶，methylglyoxal reductase）]] | [[乙二醛酶I（glyoxylase I）]] | | 4 | [[乙醛脱氢酶（aldehyde dehydrogenase）]] | [[乙二醛酶II（glyoxylase II）]] | | 5 | [[L-乳酸脱氢酶（L-LDH）]] | [[D-乳酸脱氢酶（D-LDH）]] |