第1次脱氢
称谓
异柠檬酸脱氢酶 IDH
催化反应
[[C6：异柠檬酸（isocitric）]]+^+$-->[[C5：α-酮戊二酸（α-Ketoglutaric acid，AKG）]]++H^+$+$
$化学方程式：$
-
\usepackage{chemfig}
\begin{document}
\chemfig{
CH
(-[,0.5]COO^{-})
(-[2,0.5]CH_2-[,0.5]COO^{-})
(-[6,0.5]CH
(-[,0.5]COO^{-})
(-[4,0.5]HO)
)
}
+
\chemfig{
NAD^+
}
\begin{tikzpicture}
\draw [->] (0,0) to node[above] {IDH} (1,0); % 水平箭头
\end{tikzpicture}
\chemfig{
CH_2
(-[2,0.5]CH_2-[,0.5]COO^{-})
(-[6,0.5]C
(-[,0.5]COO^{-})
(=[6,0.5]O)
)
}
+\chemfig{
NADH+H^+
}
+\chemfig{
CO_2
}
+2.5ATP
\end{document}-
\usepackage{chemfig}
\begin{document}
\chemfig{
CH
(-[,0.5]COOH)
(-[2,0.5]CH_2-[,0.5]COOH)
(-[6,0.5]CH
(-[,0.5]COOH)
(-[4,0.5]HO)
)
}
+
\chemfig{
NAD^+
}
\begin{tikzpicture}
\draw [->] (0,0) to node[above] {IDH} (1,0); % 水平箭头
\end{tikzpicture}
\chemfig{
CH_2
(-[2,0.5]CH_2-[,0.5]COOH)
(-[6,0.5]C
(-[,0.5]COOH)
(=[6,0.5]O)
)
}
+\chemfig{
NADH+H^+
}
+\chemfig{
CO_2
}
+2.5ATP
\end{document}-
\usepackage{chemfig}
\begin{document}
\chemfig{
(<[4,0.5]
(=[3,0.5]O)
(-[4.5,0.5]HO)
)
(-[1.5,0.5]
(-[3,0.5]
(=[4,0.5]O)
(-[1.5,0.5]OH)
)
)
(-[7,0.5]
(<[,0.8]OH)
(-[5,0.5]
(=[4,0.5]O)
(-[7,0.5]OH)
)
)
}
+
\chemfig{
NAD^+
}
\begin{tikzpicture}
\draw [->] (0,0) to node[above] {IDH} (1,0); % 水平箭头
\end{tikzpicture}
\chemfig{
(-[7.5,0.5]OH)
(=[2,0.5]O)
(-[4.5,0.5]
(-[3.5,0.5]
(-[4.5,0.5]
(=[6,0.5]O)
(-[3.5,0.5]
(=[2,0.5]O)
(-[4.5,0.5]HO)
)
)
)
)
}
+\chemfig{
NADH+H^+
}
+\chemfig{
CO_2
}
+2.5ATP
\end{document}-
O=C(O)C(CC(=O)O)C(O)C(=O)O>>
O=C(O)C(=O)CCC(=O)O.
C(=O)=O下一步
[[4. TAC：α-酮戊二酸氧化脱羧：α-酮戊二酸脱氢酶（KGDH）]]