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C5：α-酮戊二酸（α-Ketoglutaric acid，AKG）

α-酮戊二酸 α-Ketoglutaric acid alpha-ketoglutarate α-KG AKG smiles C CC =O O C =O C =O O $结构式：$ - tikz \usepackage chemfig \begin document \chemfig C - 2,1 COOH = 4,1 O - 6,1 CH 2

作者：admin

2026-08-16

称谓

α-酮戊二酸 α-Ketoglutaric acid alpha-ketoglutarate α-KG AKG

3D结构

C(CC(=O)O)C(=O)C(=O)O

$结构式：$ -

\usepackage{chemfig}
\begin{document}
\chemfig{
C
	(-[2,1]COOH)
	(=[4,1]O)
	(-[6,1]CH_2
		-[5,1]
		(-[7,1]COOH)
	)
}
\end{document}

\usepackage{chemfig}
\begin{document}
\chemfig{
C
	(-[2,1]COOH)
	(=[4,1]O)
	(-[6,1]CH_2
		-[6,1]CH_2
		(-[6,1]COOH)
	)
}
\end{document}

\usepackage{chemfig}
\begin{document}

\chemfig{
	CH_2
		(-[2,0.5]CH_2-[,0.5]COO^{-})
		(-[6,0.5]C
			(-[,0.5]COO^{-})
			(=[6,0.5]O)
		)
}

\end{document}

\usepackage{chemfig}
\begin{document}

\chemfig{
	CH_2
		(-[2,0.5]CH_2-[,0.5]COOH)
		(-[6,0.5]C
			(-[,0.5]COOH)
			(=[6,0.5]O)
		)
}

\end{document}

\usepackage{chemfig}
\begin{document}

\chemfig{
	(-[7.5,0.5]OH)
	(=[2,0.5]O)
	(-[4.5,0.5]
		(-[3.5,0.5]
			(-[4.5,0.5]
				(=[6,0.5]O)
				(-[3.5,0.5]
					(=[2,0.5]O)
					(-[4.5,0.5]HO)
				)
			)
		)
	)
}

\end{document}

O=C(O)C(=O)CCC(=O)O

产生

[[3. TAC：异柠檬酸氧化脱羧：异柠檬酸脱氢酶（IDH）]] [[谷草转氨酶（aspartate aminotransferase，AST）]]

参与反应

[[4. TAC：α-酮戊二酸氧化脱羧：α-酮戊二酸脱氢酶（KGDH）]]